null
SMILES CN(Cc1ccc(F)cc1)C(=O)[C@@H](NC(=O)c1ccc2nc(NC(=O)c3ccccc3-c3ccc(cc3)C(C)(C)C)ccc2c1)c1ccccc1
InChI Key InChIKey=UDPREAJJGGXUGR-KDXMTYKHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50391864
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 0nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair