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SMILES Nc1cccc(c1)-c1cnc2[nH]cc(-c3cccnc3)c2c1

InChI Key InChIKey=YWOJRGRRNWQSOH-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50391956   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
UiT The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataKd:  4.50E+3nMAssay Description:Binding affinity to PI3Kalpha by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
UiT The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataIC50: 329nMAssay Description:Inhibition of DYRK1A (unknown origin) measured after 6 hrs in presence of ATP by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataKd:  75nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2BQ3PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
UiT The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50391956(CHEMBL2152265)copy SMILEScopy InChI
Affinity DataIC50: 329nMAssay Description:Inhibition of DYRK1A (unknown origin) using DYRKtide as substrate by ATP regenerative NADH consuming assayMore data for this Ligand-Target Pair