null

SMILES OCCOc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1

InChI Key InChIKey=BEBRVWJJIIYATD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392171   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JTJPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)copy SMILEScopy InChI
Affinity DataIC50: 583nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University

Curated by ChEMBL
LigandPNGBDBM50392171(CHEMBL2152940)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4JTJPubMed