null

SMILES CC(C)Oc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](C)c3ccc(F)cn3)nc12

InChI Key InChIKey=FZBVNCFBCNXULH-LBPRGKRZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50392791   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca AB

US Patent
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:JAK2 and Trk A kinase activity was determined by measuring the kinase's ability to phoshorylate synthetic tyrosine residues within a generic poly...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0K7XUS Patent
TargetSerine/threonine-protein kinase WNK3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 99.8nMAssay Description:Inhibition of WNK3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Astrazeneca AB

US Patent
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TrkAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FgrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetSerine/threonine-protein kinase SIK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of SIKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of PhKg2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 13.4nMAssay Description:Inhibition of SAPK2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 17.2nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 18.2nMAssay Description:Inhibition of cSrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTestis-specific serine/threonine-protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 30.6nMAssay Description:Inhibition of TSSK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 34.1nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 44.3nMAssay Description:Inhibition of MLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 68.3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 72.2nMAssay Description:Inhibition of ItkMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392791(CHEMBL2151321 | US8486966, 1)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9K2GPubMed