null

SMILES CNC(=O)c1nc(cnc1N)-c1cccc(c1)S(=O)(=O)Nc1cccc(F)c1F

InChI Key InChIKey=FIMDHTYPJGAISK-UHFFFAOYSA-N

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50393361   

LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 102nMAssay Description:Inhibition of human PI3Kgamma expressed in sf9 cells assessed as amount of ATP consumed by luciferase-luciferin chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human PI3Kalpha expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human PI3Kgamma expressed in C5a-stimulated mouse RAW 264.7 cells assessed as inhibition of AKT phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human PI3Kdelta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed
LigandPNGBDBM50393361(CHEMBL2152251)copy SMILEScopy InChI
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of human PI3Kbeta expressed in sf9 cells coexpressing p85alpha assessed as amount of ATP consumed by luciferase-luciferin chemiluminescenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6S9NPubMed