null
SMILES FC(F)(F)Oc1ccc(CNC(=O)C2N(CCC3CCOCC3)C(=O)c3ccccc23)cc1
InChI Key InChIKey=LWAACTJZSQSIBS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50395325
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca
Curated by ChEMBL
AstraZeneca
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Binding affinity to human ERG expressed in CHOK1 cells by IonWorks HT assayMore data for this Ligand-Target Pair