null

SMILES Cc1cccc2C(=O)N(CCc3ccccn3)C(C(=O)NCc3ccc(OC(F)(F)F)cc3)c12

InChI Key InChIKey=NARGIHUYNYFIGB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395345   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50395345(CHEMBL2164369)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Binding affinity to human ERG expressed in CHOK1 cells by IonWorks HT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909SBPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50395345(CHEMBL2164369)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909SBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50395345(CHEMBL2164369)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909SBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50395345(CHEMBL2164369)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M909SBPubMed