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SMILES CSc1nn2c3CCN(C)Cc3cnc2c1S(=O)(=O)c1ccccc1

InChI Key InChIKey=SLKVTBZWWJECHL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396228   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50396228(CHEMBL2172183 | US8569318, 1.2(3))copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PZ8PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50396228(CHEMBL2172183 | US8569318, 1.2(3))copy SMILEScopy InChI
Affinity DataKi:  14.8nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HE293 cells assessed as inhibition of serotonin-induced cAMP accumulation after 2...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5PZ8PubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50396228(CHEMBL2172183 | US8569318, 1.2(3))copy SMILEScopy InChI
Affinity DataKi:  35.7nM IC50: 76.9nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3JT8US Patent