null
SMILES C[C@@H]1CN([C@@H](CO1)c1ccccc1)c1ccc2OCC(=O)Nc2n1
InChI Key InChIKey=NDBQYPUELRHJBZ-OCCSQVGLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50398061
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-aldosterone to human mineralocorticoid receptor LBD by radiometric binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human GAL4-DBD fused AR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PR (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-progesterone from recombinant human His-tagged PR-b after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to AR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at GR (unknown origin) by Gal4-based cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]-aldosterone from human GST-tagged MR ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-dexamethasone from recombinant human GST-tagged GR ligand binding domain after 4 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Antagonist activity at human GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at rat GAL4-DBD fused MR ligand binding domain transfected in human Huh7 cells co-expressing GAL4-RE-Luc assessed as reduction in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to ERalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at gal4-fused human mineralocorticoid receptor LBD expressed in UAS-MR-bla HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 597nMAssay Description:Binding affinity to GR (unknown origin) expressed in human IM9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at mineralocorticoid receptor in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at Gal4-fused MR LBD (unknown origin) expressed in human Huh7 cells assessed as inhibition of aldosterone-induced transcriptional...More data for this Ligand-Target Pair