null

SMILES COc1ccccc1NC(=O)N(CCCN(C)C)Cc1ccc(cc1)C(=O)NO

InChI Key InChIKey=RGZUDRIVUNALGI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50398726   

TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5CWNUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 458nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21V5CWNUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Sf9 cells incubated for 2 hrs using RHKK-Ac fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04XPPubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of human recombinant HDAC1 expressed in Sf9 cells incubated for 2 hrs using RHKK-Ac fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04XPPubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ68CWUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9KBRUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD71RFUS Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 458nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD71RFUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ68CWUS Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center and Research Institute, Inc.; Board of Trustees of the University of Illinois

US Patent
LigandPNGBDBM50398726(CHEMBL2179248 | US10227295, Compound 5a | US940985...)copy SMILEScopy InChI
Affinity DataIC50: 2.55E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23T9KBRUS Patent