null
SMILES O=C(Nc1ccccn1)Nc1cccc2C(=O)N3CCCCC3c12
InChI Key InChIKey=KVVMSGAISWJACO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50399301
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£ d'Orl£ans
Curated by ChEMBL
Universit£ d'Orl£ans
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate and [gamma-33P]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£ d'Orl£ans
Curated by ChEMBL
Universit£ d'Orl£ans
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST fused human recombinant DYRK1A expressed in Escherichia coli using woodtide as substrate after 30 mins by scintillation counting in...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of native porcine brain GSK-3alpha/beta using GS-1 as substrate incubated for 30 mins in presence of [gamma-33P]ATP by liquid scintillatio...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Universit£ d'Orl£ans
Curated by ChEMBL
Universit£ d'Orl£ans
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma-33P]-ATP after 30 mins by...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£ d'Orl£ans
Curated by ChEMBL
Universit£ d'Orl£ans
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate in presence of [gamma-33P]ATP incubated for 30 mins by liquid scintillation co...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£ d'Orl£ans
Curated by ChEMBL
Universit£ d'Orl£ans
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrateMore data for this Ligand-Target Pair