null
SMILES Cc1cccc(n1)N1CCN(CC1)C(=O)[C@H](CCCCNC(=O)C=C)NC(=O)Cc1ccccc1
InChI Key InChIKey=CLPJEHNKARSBTP-QHCPKHFHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50400621
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataKi: 5.73E+3nMAssay Description:Reversible inhibition of human TGase 2 using Z-Glu(HMC)-Gly-OH as substrate measured at 20 secs interval over 900 secs by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of coagulation factor 13aMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of transglutaminase 6More data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of TGase 2 in human A375 cells using R-I-Cad/DMC as substrate preincubated for 5 mins followed by substrate addition measured at 30 secs i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of transglutaminase 1More data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human TGase 2 using R-I-Cad/DMC as substrate preincubated for 5 mins followed by substrate addition measured at 30 secs interval over 9...More data for this Ligand-Target Pair
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Irreversible inhibition of transglutaminase 2More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of transglutaminase 3More data for this Ligand-Target Pair