null

SMILES Cc1cccc(n1)N1CCN(CC1)C(=O)[C@H](CCCCNC(=O)C=C)NC(=O)Cc1ccccc1

InChI Key InChIKey=CLPJEHNKARSBTP-QHCPKHFHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50400621   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataKi:  5.73E+3nMAssay Description:Reversible inhibition of human TGase 2 using Z-Glu(HMC)-Gly-OH as substrate measured at 20 secs interval over 900 secs by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66PC7PubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of coagulation factor 13aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1823PubMed
TargetProtein-glutamine gamma-glutamyltransferase 6(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of transglutaminase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1823PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of TGase 2 in human A375 cells using R-I-Cad/DMC as substrate preincubated for 5 mins followed by substrate addition measured at 30 secs i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66PC7PubMed
TargetProtein-glutamine gamma-glutamyltransferase K(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of transglutaminase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1823PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of human TGase 2 using R-I-Cad/DMC as substrate preincubated for 5 mins followed by substrate addition measured at 30 secs interval over 9...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66PC7PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Helmholtz-Zentrum Dresden-Rossendorf

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Irreversible inhibition of transglutaminase 2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1823PubMed
TargetProtein-glutamine gamma-glutamyltransferase E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400621(CHEMBL2203451)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of transglutaminase 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1823PubMed