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SMILES Cc1csc(n1)-c1[nH]cnc1-c1ccc2ncsc2c1

InChI Key InChIKey=LLFCXRYULHMNCG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50402166   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50402166(CHEMBL2207988)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of ALK5-mediated TNFalpha-induced Smad2/3 phosphorylation in human A549 cells preincubated for 2 hrs before addition of TNFalpha after 1 h...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542PQ0PubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))TBA
LigandPNGBDBM50402166(CHEMBL2207988)copy SMILEScopy InChI
Affinity DataIC50: 836nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50402166(CHEMBL2207988)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50402166(CHEMBL2207988)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human ALK5 using GST-tagged Smad3 as substrate assessed as substrate phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542PQ0PubMed