null

SMILES Nc1ncc(Cc2cccc(c2)C(F)(F)F)c(N)n1

InChI Key InChIKey=ULJLXZHDPJDSAN-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50405976   

TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2S6TPubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JTCPubMed
TargetDihydrofolate reductase(Salmonella enterica subsp. enterica serovar Typhi)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X92CH4PubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  95nMAssay Description:Compound is evaluated for the inhibition of dihydrofolate reductase from Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WQMPubMed
TargetDihydrofolate reductase(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  95.5nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QQJPubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  692nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4ZB9PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  692nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WH2S6TPubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  1.66E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  1.66E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Bos taurus (Cattle))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  2.95E+3nMAssay Description:Inhibition of dihydrofolate reductase from bovine liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WQMPubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4ZB9PubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50405976(CHEMBL19790)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DF6TDDPubMed