null

SMILES Cc1ccc2c(cccc2n1)N1CCN(CCc2cccc3NC(=O)COc23)CC1

InChI Key InChIKey=DSRZHYGLARQICV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50413549   

Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  0.0501nMAssay Description:Antagonist activity at human 5HT1D assessed as GTPgammaS binding by scintillation proximity assay in presence of 5-HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J967MXPubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  0.0501nMAssay Description:Antagonist activity at human 5-HT1D receptor expressed in CHO cells assessed as inhibition of GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC919VPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  0.251nMAssay Description:Antagonist activity at human 5HT1A assessed as GTPgammaS binding by scintillation proximity assay in presence of 5-HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J967MXPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  0.251nMAssay Description:Antagonist activity at human 5-HT1A receptor expressed in HEK293 cells assessed as inhibition of GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC919VPubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Antagonist activity at human 5-HT1B receptor expressed in CHO cells assessed as inhibition of GTPgammaS binding by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC919VPubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Antagonist activity at human 5HT1B assessed as GTPgammaS binding by scintillation proximity assay in presence of 5-HTMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J967MXPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Displacement of [3H]-citalopram in human SERT expressed in LLCPK cells by filtration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC919VPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Displacement of [3H]citalopram human SerT receptor expressed in LLCPK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J967MXPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]dofetilide human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J967MXPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50N6MPubMed
TargetTranscriptional regulator ERG(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50413549(CHEMBL513715)copy SMILEScopy InChI
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-dofetilide in human ERG expressed in CHO cells by proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC919VPubMed