null

SMILES CCc1cccc(NC(=O)Nc2cccn(Cc3ccccc3Cl)c2=O)c1

InChI Key InChIKey=MYTRTEZPNKENOK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50417192   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi:  50.1nMAssay Description:Antagonist activity at human EP3 receptor expressed in human U2OS cells assessed as inhibition of PGE2-induced intracellular calcium mobilization by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetProstaglandin E2 receptor EP3 subtype(RAT)
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi:  158nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human TP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human FP receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50417192(CHEMBL1271476)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M65Z8PubMed