null

SMILES Nc1nccc2cc(O[C@H]3CCCN(Cc4ccccc4)C3)ccc12

InChI Key InChIKey=IZFFAYAQVHNZHH-IBGZPJMESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50417667   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataKi:  794nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 91.2nMAssay Description:Inhibition of ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of ROCK-1 by Immobilized metal ion affinity-based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0GQKPubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
MSD

Curated by ChEMBL
LigandPNGBDBM50417667(CHEMBL1643574)copy SMILEScopy InChI
Affinity DataIC50: 776nMAssay Description:Inhibition of ROCK1 in human THP cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN468GPubMed