null
SMILES CCS(=O)(=O)N1CCC(CC1)c1c[nH]c2c(cc(cc12)-c1ccccc1)C(N)=O
InChI Key InChIKey=UCPWBEUDVDWSCD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50418167
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IKK-alphaMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.
Curated by ChEMBL
GlaxoSmithKline Inc.
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of IKKbeta in human CD14-positive monocytes assessed as reduction in LPS-stimulated TNFalpha secretion preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.
Curated by ChEMBL
GlaxoSmithKline Inc.
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.
Curated by ChEMBL
GlaxoSmithKline Inc.
Curated by ChEMBL
Affinity DataIC50: 25.1nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair