null

SMILES CCS(=O)(=O)N1CCC(CC1)c1c[nH]c2c(cc(cc12)-c1ccccc1)C(N)=O

InChI Key InChIKey=UCPWBEUDVDWSCD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50418167   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50418167(CHEMBL1761514)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of IKK-alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.

Curated by ChEMBL
LigandPNGBDBM50418167(CHEMBL1761514)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of IKKbeta in human CD14-positive monocytes assessed as reduction in LPS-stimulated TNFalpha secretion preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1V1HPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.

Curated by ChEMBL
LigandPNGBDBM50418167(CHEMBL1761514)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SHGPubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
GlaxoSmithKline Inc.

Curated by ChEMBL
LigandPNGBDBM50418167(CHEMBL1761514)copy SMILEScopy InChI
Affinity DataIC50: 25.1nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VS3PubMed