null

SMILES C=CC(=O)Nc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=NWFPBQYIKXKLNF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50420459   

TargetProtein-glutamine gamma-glutamyltransferase 6(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant TG6 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Mus musculus)
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human TG2 in HEK cells by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Ability to inhibit U-46,619-induced contraction of isolated strips of rabbit thoracic aorta, which is the measure of thromboxane receptor antagonismMore data for this Ligand-Target Pair
In DepthDetails
TargetProtein-glutamine gamma-glutamyltransferase K(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant TG1 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetProtein-glutamine gamma-glutamyltransferase E(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of thrombin activated human TG3 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetCoagulation factor XIII A chain(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of thrombin activated human F13a by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Evotec (UK) Ltd.

Curated by ChEMBL
LigandPNGBDBM50420459(CHEMBL2086528)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant TG2 by fluorescent transamidation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7560PubMed