null

SMILES COCCCc1cc(Nc2ccnc(NCc3cc(C)no3)n2)[nH]n1

InChI Key InChIKey=QSABFBQRTHXLQJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420939   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50420939(CHEMBL2088099)copy SMILEScopy InChI
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant N terminal His6-tagged human IGF1R (959 to end) expressed in baculovirus infected Sf21 cells after 80 mins by caliper mobil...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B62PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50420939(CHEMBL2088099)copy SMILEScopy InChI
Affinity DataIC50: 79.4nMAssay Description:Inhibition of recombinant N terminal GST-tagged human FGFR1 (456 to 765) expressed in baculovirus infected Sf21 cells after 40 mins by caliper mobili...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B62PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50420939(CHEMBL2088099)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of recombinant N terminal GST-tagged human KDR (805 to 1356) expressed in baculovirus infected Sf9 cells after 90 mins by caliper mobility...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2B62PubMed