null

SMILES Fc1cccc(c1)C(=C1C(=O)Nc2ccccc12)c1nc2ccccc2[nH]1

InChI Key InChIKey=MEVPRNFNZQYFKY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421001   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50421001(CHEMBL2086725)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Inhibition of N-terminal GST-tagged KDR after 4 hrs by luciferase-luciferin coupled chemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SD4PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50421001(CHEMBL2086725)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of N-terminal GST-tagged FGFR1 using poly(Glu,Tyr) as substrate after 30 mins by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SD4PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Exelixis

Curated by ChEMBL
LigandPNGBDBM50421001(CHEMBL2086725)copy SMILEScopy InChI
Affinity DataIC50: 522nMAssay Description:Inhibition of N-terminal GST-tagged Flt1 using poly(Glu,Tyr) as substrate after 60 mins by alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9SD4PubMed