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SMILES NCCSc1nc2ccccc2o1

InChI Key InChIKey=LIZDKHZOMRDDRY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421231   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Gedeon Richter Plc., Gy�mroi�t 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50421231(CHEMBL2087646)copy SMILEScopy InChI
Affinity DataKi:  646nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM892TPubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
University of Texas

Curated by ChEMBL
LigandPNGBDBM50421231(CHEMBL2087646)copy SMILEScopy InChI
Affinity DataKi:  1.70E+6nMAssay Description:Competitive inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZBJPubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
University of Texas

Curated by ChEMBL
LigandPNGBDBM50421231(CHEMBL2087646)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+6nMAssay Description:Inhibition of human recombinant His6-tagged DDAH1 expressed in Escherichia coli BL21(DE3) using Nomega,Nomega-dimethyl-L-arginine as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416ZBJPubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Gedeon Richter Plc., Gy�mroi�t 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50421231(CHEMBL2087646)copy SMILEScopy InChI
Affinity DataEC50:  3.16E+3nMAssay Description:Agonist activity at recombinant human alpha2c adrenergic receptor expressed in CHOK1 cells co-expressing Gqi5 assessed as induction of cytoplasmic ca...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM892TPubMed