null

SMILES Nc1c(cnn1-c1ccc(F)cc1F)C(=O)NCC(O)(CC1(CCCc2ccccc12)C1CCCC1)C(F)(F)F

InChI Key InChIKey=FLEMAWPZKNFCDI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50423196   

TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423196(CHEMBL235205)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423196(CHEMBL235205)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423196(CHEMBL235205)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423196(CHEMBL235205)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50423196(CHEMBL235205)copy SMILEScopy InChI
Affinity DataIC50: 275nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells transfected with MMTV luciferase reporter gene assessed as inhibition of dexametha...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD206GPubMed