null

SMILES Cc1cc(OCCCc2c(C(O)=O)n(C)c3cc(Cl)ccc23)cc(C)c1Cl

InChI Key InChIKey=MRXZHJUTVZJIGX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50424749   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424749(CHEMBL2314171 | US11760752, Compound Fesik Indole)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Displacement of FITC-AHx-KALETLRRVGDGVQRNHETAF-NH2 from human MCl1 (172 to 327) expressed in Escherichia coli BL21 (DE3) after 1 hr by fluorescence p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5P46PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424749(CHEMBL2314171 | US11760752, Compound Fesik Indole)copy SMILEScopy InChI
Affinity DataKi:  247nMMore data for this Ligand-Target Pair
In DepthDetails
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50424749(CHEMBL2314171 | US11760752, Compound Fesik Indole)copy SMILEScopy InChI
Affinity DataKi:  247nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50424749(CHEMBL2314171 | US11760752, Compound Fesik Indole)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))TBA
LigandPNGBDBM50424749(CHEMBL2314171 | US11760752, Compound Fesik Indole)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails