null

SMILES COc1cc2Nc3[nH]nc(C)c3N=C(c3ccccc3Cl)c2cc1F

InChI Key InChIKey=UOVCGJXDGOGOCZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50426474   

TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
EntreMed Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of human PLK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM59V9PubMed
TargetAurora kinase A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
EntreMed Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0MHVPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0MHVPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0MHVPubMed
TargetAurora kinase A(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0MHVPubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))TBA
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Hoffmann-La Roche Inc.

Curated by ChEMBL
LigandPNGBDBM50426474(CHEMBL1980391)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2902541PubMed