null
SMILES O=c1cc(oc2c(csc12)-c1ccccc1)N1CCOCC1
InChI Key InChIKey=ROWRIIZUTZDVNX-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50427454
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 2.17E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Pfizer
Pfizer
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 297nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 378nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 784nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Pfizer
Pfizer
Affinity DataIC50: 1.57E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
The University of Arizona
Curated by ChEMBL
The University of Arizona
Curated by ChEMBL
Affinity DataIC50: 610nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 378nMAssay Description:Inhibition of PI3K p110beta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 297nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Pfizer
Pfizer
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 784nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 297nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 784nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 3.45E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair