null
SMILES Nc1cccc(c1)-c1csc2c1oc(cc2=O)N1CCOCC1
InChI Key InChIKey=JMTOJRFMAPIYKE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50427476
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 843nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 1.74E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 154nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 9.81E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 6.30E+3nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of PI3K p110gamma (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 9.81E+3nMAssay Description:Inhibition of PI3K p110delta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 843nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 9.81E+3nMAssay Description:Inhibitory activity can be determined routinely using known methods and also from commercial vendors offering this service for kinases and bromodomai...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
SignalRx Pharmaceuticals, Inc.
US Patent
SignalRx Pharmaceuticals, Inc.
US Patent
Affinity DataIC50: 154nMAssay Description:Inhibition of PI3K p110alpha (unknown origin)More data for this Ligand-Target Pair