null

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cncc4nccn34)cc2C(F)(F)F)CC1

InChI Key InChIKey=VSJSIOZQNZPUAV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50427749   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of P38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of wild type Abl1 kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Abl1 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Cyclofluidic Ltd

Curated by ChEMBL
LigandPNGBDBM50427749(CHEMBL2324924)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Abl2 kinase (unknown origin) using Tyr 6 peptide as substrate assessed as residual enzyme activity after every 10 secs measured for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6KPDPubMed