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SMILES Oc1cc(CCC2CCCCC2)n[nH]c1=O

InChI Key InChIKey=XOTMJYKZULIBIT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50431075   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.4 T: 2°CAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SW0US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6GCRUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542QQDUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76FWCUS Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

US Patent
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2BXGUS Patent
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma Inc.

Curated by ChEMBL
LigandPNGBDBM50431075(CHEMBL2338789 | US10202399, Example 40 | US1046366...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2QPZPubMed