null

SMILES CN1C(N)=NC2(CC(C)(C)Sc3ccc(cc23)-c2cccc(c2)C#N)C1=O

InChI Key InChIKey=BHAHIONIGQVZOZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50432529   

TargetBeta-secretase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50432529(CHEMBL2349474)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant BACE1 expressed in CHO cells using biotin-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4Z52PubMed
TargetCathepsin D(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50432529(CHEMBL2349474)copy SMILEScopy InChI
Affinity DataIC50: 603nMAssay Description:Inhibition of human spleen cathepsin D using 5-FAM/QXL as peptide substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4Z52PubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Array BioPharma

Curated by ChEMBL
LigandPNGBDBM50432529(CHEMBL2349474)copy SMILEScopy InChI
Affinity DataEC50:  58nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing wild type APP assessed as level of amyloid beta (1 to 40) after 48 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4Z52PubMed