null
SMILES CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NO)-c1ccccc1
InChI Key InChIKey=LCQMZRDBGJAUEU-KAYWLYCHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50432559
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 9.20nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 118nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 467nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 83.7nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant HMG-CoA reductase (unknown origin) after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 467nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 123nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
ACADEMIA SINICA; NATIONAL TAIWAN UNIVERSITY
US Patent
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of HMG-CoA reductase in human A549 cells after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair