null
SMILES C[C@@H]1C[C@H](OC(=O)Nc2ccc(cc2)-c2cn(CCCCCCC(=O)NO)nn2)[C@@H]2[C@@H](CC[C@@H]3C[C@H](CC(=O)O3)O[Si](C)(C)C(C)(C)C)[C@@H](C)C=CC2=C1
InChI Key InChIKey=YNBGBSUCOIHSSU-DZVBGLRJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50432564
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 36.5nMpH: 7.4Assay Description:The HMGR activity was performed using HMG-CoA reductase assay kit from Sigma-Aldrich with the human recombinant protein or 100 μg total cell lys...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 159nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 463nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 127nMT: 2°CAssay Description:The HDAC activity was performed using the HDAC fluorescent activity assay kit (BIOMOL, Plymouth Meeting, Pa., USA) according to the manufacturer'...More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant HMG-CoA reductase (unknown origin) after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 463nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Academia Sinica; National Taiwan University
US Patent
Academia Sinica; National Taiwan University
US Patent
Affinity DataIC50: 2.23E+4nMAssay Description:Inhibition of HMG-CoA reductase in human A549 cells after 5 mins by spectrophotometric analysisMore data for this Ligand-Target Pair