null
SMILES CC(C)n1ncnc1-c1nc-2c(CCOc3cc(ccc-23)C2CNC2)s1
InChI Key InChIKey=UYNXWBXISXVSIW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50433521
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of GST-fused human recombinant PI3Kbeta expressed in baculovirus infected SF9 cells after 1 hr by scintillation proximity assay in presenc...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of GST-fused human recombinant PI3Kgamma expressed in baculovirus infected SF9 cells after 1 hr by scintillation proximity assay in presen...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech, Inc.
Curated by ChEMBL
Genentech, Inc.
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3Kalpha in human PC3 cells assessed as inhibition of AKT phosphorylation at Ser473 after 2 hrs by ELISAMore data for this Ligand-Target Pair