null
SMILES O=C(CNC(=O)c1ccnc2ccccc12)N1CCC[C@H]1C#N
InChI Key InChIKey=MTHMMXFBHKGAAI-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50434188
Affinity DataKi: 3nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SF-tagged DPP4 (unknown origin) expressed in Drosophila S2 cells using fluorogenic substrate by spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 860nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 8.35E+4nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 860nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP2 purified from human seminal plasma using Lys-Ala-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant mouse FAP purified from HEK293 cell supernatant using Ala-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant human PREP purified from Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP4 purified from human seminal plasma using Gly-Pro-p-nitroanilide as substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetProlyl endopeptidase(Homo sapiens (Human))
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Universiteit Antwerp; Fox Chase Cancer Center
US Patent
Affinity DataIC50: 860nMAssay Description:Inhibition of human recombinant PREP expressed in Escherichia coli using Z-Gly-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substra...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells using Ala-Pro-p-nitroanilide as substrate incubated for 15 mins prior to substrate addi...More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of SF-tagged FAP (unknown origin) expressed in Drosophila S2 cells using fluorogenic substrate by spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
Affinity DataIC50: 10.3nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair