null

SMILES COC(=N)c1nc2ccc3ncnc(Nc4ccc(C)cc4)c3c2s1

InChI Key InChIKey=AVKKQBJQERVCTD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50434364   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610Z7JUS Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 2.83nMpH: 7.5 T: 2°CAssay Description:The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2610Z7JUS Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMAssay Description:Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GDPPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DP7PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human DYRK1A using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9NMGPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human DYRK1B using [33P]-ATP incubated for 120 minsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9NMGPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 0.980nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90DP7PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
DIAXONHIT

US Patent
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GDPPubMed