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SMILES CNC(=O)CN1CCC(CC1)Oc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC

InChI Key InChIKey=DFJSJLGUIXFDJP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50437353   

TargetCytochrome P450 2D6(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82JHPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82JHPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82JHPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N82JHPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human EFGR expressed in baculovirus/Sf21 system by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human HER2 expressed in baculovirus/Sf21 system in presence of ATP by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N548XPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stim...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4NVJPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human HER2 expressed in baculovirus/Sf21 system by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human HER3 expressed in baculovirus/Sf21 system by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474F5DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech Co. Ltd.

Curated by ChEMBL
LigandPNGBDBM50437353(CHEMBL2408045)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human EGFR expressed in baculovirus/Sf21 system in presence of ATP by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N548XPubMed