null

SMILES CCCN(Cc1nc2CCOCc2c(=O)[nH]1)C(=O)CN1CCC(CC1)C(=O)c1ccc(F)cc1

InChI Key InChIKey=CCVBOAMGJQRBBT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50439795   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 46nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P0XTFUS Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P0XTFUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P0XTFUS Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PARP1 (unknown origin) assessed as nicotinamide concentration by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PARP2 (unknown origin) assessed as nicotinamide concentration by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WFBPubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439795(CHEMBL2419702 | US9181266, 34)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P0XTFUS Patent