null
SMILES FC(F)(F)c1ccc(cc1)-c1nc2ccccc2c(=O)[nH]1
InChI Key InChIKey=LSKQRMBPLLMJRR-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50439825
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 133nMAssay Description:Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrat...More data for this Ligand-Target Pair
3D Structure (crystal)TargetProtein Wnt-3a(Homo sapiens (Human))
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Novartis Institutes for Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University of Bath
Curated by ChEMBL
University of Bath
Curated by ChEMBL
Affinity DataIC50: 425nMAssay Description:Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair