null

SMILES CN1CCN(CC1)C(=O)[C@H](CNC(=O)c1ccc(Cl)s1)NS(=O)(=O)c1cccc(N2CCCC2=O)c1C

InChI Key InChIKey=CYVVCTRDWISRAC-KRWDZBQOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50443853   

TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2B0CPubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of t-PA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2B0CPubMed
TargetPlasminogen(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2B0CPubMed
TargetCoagulation factor XI(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetSerine protease 1(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPlasminogen(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetKallikrein-1(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 0.430nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCoagulation factor X(Homo sapiens (Human))
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2B0CPubMed
TargetProthrombin(Homo sapiens (Human))TBA
LigandPNGBDBM50443853(CHEMBL3091519 | US20230391761, Reference 1)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
In DepthDetails