null

SMILES Cc1cc(ccc1[C@H]1CCc2cncn12)C#N

InChI Key InChIKey=LQBBLIGVEXCCQK-CQSZACIVSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50444548   

TargetCytochrome P450 11B1, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 386nMAssay Description:Inhibition of rat recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant CYP11B1 using 11-deoxycortisol as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed
TargetCytochrome P450 11B2, mitochondrial(Rattus norvegicus)
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50444548(CHEMBL3099696)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of rat recombinant CYP11B2 using 11-deoxycorticosterone as substrate by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8938PubMed