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SMILES Clc1cccc2N(CCc12)C(=O)Cc1nc(cc(=O)[nH]1)N1CCOCC1

InChI Key InChIKey=IADWZPWKRCWMPE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50447089   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473 (P-AKT-S473), in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9V9PUS Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kbeta expressed in baculovirus-infected sf21 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kalpha expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of N-terminal ploy-His-tagged human PI3Kdelta expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed
LigandPNGBDBM50447089(CHEMBL3112849)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of C-terminal ploy-His-tagged human PI3Kgamma expressed in baculovirus-infected sf9 cells using PI(4,5)P2 as substrate after 15 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R212VJPubMed