null

SMILES CNc1nc(Nc2cnn3CCOCc23)ncc1C(F)(F)F

InChI Key InChIKey=LLTDZFXQHNQWKA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50448125   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM50448125(CHEMBL3122106 | US9212186, 17)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 3...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SPXUS Patent
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM50448125(CHEMBL3122106 | US9212186, 17)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0181NPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM50448125(CHEMBL3122106 | US9212186, 17)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N0181NPubMed