null
SMILES Cc1noc(C)c1-c1ccc(cc1)C(=O)N1[C@@H](CS[C@@H]1c1ccccc1Cl)C(O)=O
InChI Key InChIKey=RZAMDGBOOPJHJQ-GHTZIAJQSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50450263
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataKi: 204nMAssay Description:Displacement of [3H]-GLPG0974 from human FFA2 expressed in Flp-InT-REx 293 cell membranes after 2 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 794nMAssay Description:Agonist activity to human FFA2R expressed in HEK293T cells assessed as induction beta-arrestin-2 recruitment after 10 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.01E+3nMAssay Description:Agonist activity at FFA2R in mouse mature adipocytes assessed as inhibition of isoproterenol-induced glycerol productionMore data for this Ligand-Target Pair
TargetFree fatty acid receptor 2(Homo sapiens (Human))
University of Southern Denmark
Curated by ChEMBL
University of Southern Denmark
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Agonist activity at human FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair
Affinity DataEC50: 363nMAssay Description:Agonist activity at mouse FFA2R expressed in Flp-InT-REx 293 cells assessed as reduction of forskolin-induced cAMP production after 30 mins by TR-FRE...More data for this Ligand-Target Pair