null
SMILES Oc1c(F)cc(c2cccnc12)S(=O)(=O)C1CCCC1
InChI Key InChIKey=IVFUTUMPNJJQAQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50450452
Affinity DataIC50: 2nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development
Curated by ChEMBL
Lieber Institute for Brain Development
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged rat S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substrate...More data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Lieber Institute for Brain Development
Curated by ChEMBL
Lieber Institute for Brain Development
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of c-terminal hexa-His tagged rat MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair