null

SMILES CC(C)c1cc2cccc(-c3nnc(o3)C3CCN(CC4CCOCC4)CC3)n2n1

InChI Key InChIKey=ZFHAKBSSOYHMLY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50456121   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 2 mins in presence of NADPH-regeneration system by LC-MS/MS methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
Target5-hydroxytryptamine receptor 4(RAT)
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataEC50:  6nMAssay Description:Agonist activity at recombinant rat 5-HT4L receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase repo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at recombinant human 5-HT4E receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 12 mins in presence of NADPH-regeneration system by LC-MS/MS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Suven Life Sciences Limited

Curated by ChEMBL
LigandPNGBDBM50456121(CHEMBL4205936)copy SMILEScopy InChI
Affinity DataEC50:  6nMAssay Description:Agonist activity at recombinant human 5-HT4D receptor expressed in CHO cells assessed as induction of c-AMP accumulation after 4 hrs by luciferase re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6T32PubMed