null

SMILES COc1ccc(NC(=O)N2CCN(CC2)c2nc(N)nc3scnc23)cc1

InChI Key InChIKey=PFSGRYSHTMXMAJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50457869   

TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
UCB Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of PI4K3beta in human PBMC assessed as reduction in mitomycin-C treated human RPMI1788 cells-stimulated lymphocyte proliferation by measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W01PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
UCB Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as decrease in midazolam 1-hydroxylation by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W01PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
UCB Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of human ERG by cell based automated patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W01PubMed
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
UCB Pharma

Curated by ChEMBL
LigandPNGBDBM50457869(CHEMBL4217096)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human full length GST-tagged PI4K3beta expressed in baculovirus expression system using PI lipid kinase substrate after 60 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3W01PubMed