null

SMILES CNC(=O)c1cc(Oc2ccc3nc(N[C@@H]4CCCC[C@H]4O)sc3c2)ccn1

InChI Key InChIKey=ADZBMFGQQWPHMJ-RHSMWYFYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50460035   

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55R5SPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of CSF1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataKd:  3.40nMAssay Description:Binding affinity to human wild type CSF1R (I564 to S939 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataKd:  8.70E+3nMAssay Description:Binding affinity to human wild type FLT3 (V592 to Y969 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
In DepthDetails
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 579nMAssay Description:Inhibition of human PDGFRbeta phosphorylation in PDGF-DD induced human HEK293-TetR cells incubated for 1 hr followed by PDGF-DD stimulation and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataIC50: 155nMAssay Description:Inhibition of CSF1R phosphorylation in M-CSF induced human THP1 cells incubated for 30 mins by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))TBA
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataKd:  46nMAssay Description:Binding affinity to human wild type PDGFRbeta (V582 to Y1009 residues) expressed in bacterial expression system by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))TBA
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataKd:  210nMAssay Description:Binding affinity to human wild type PDGFRalpha (V575 to D1002 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))TBA
LigandPNGBDBM50460035(CHEMBL4227505)copy SMILEScopy InChI
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to c-Kit (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81HSSPubMed