null
SMILES COc1nc(C)c(N2CCCn3c2nc2c(Cl)ccc([C@@H](OC(F)F)C(F)(F)F)c32)c(C)n1
InChI Key InChIKey=SJCKNNGKORXNRE-MRXNPFEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50460168
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs by luc...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2alpha receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs b...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human CRF2beta receptor expressed in CHO cells assessed as inhibition of human CRF-stimulated cAMP accumulation after 4 hrs by...More data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Displacement of ovine [125-I]-CRF from human CRF1 receptor expressed in CHO cell membranes after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair