null

SMILES CC1(C)Cc2c(O1)c(cc1nc(Nc3c(Cl)cccc3Cl)[nH]c21)C(=O)Nc1cc(ccc1F)C1CC1

InChI Key InChIKey=NVDCVEDDKFLWJM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460537   

TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460537(CHEMBL4226536)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460537(CHEMBL4226536)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:Inhibition of mPGES1 in human whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460537(CHEMBL4226536)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed