null

SMILES Cn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3ccc(cc3)C3CC3)c3OC(C)(C)Cc3c12

InChI Key InChIKey=XNKWEFIDKLMLMF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460539   

TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460539(CHEMBL4225160)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of mPGES1 in human whole blood assessed as reduction in LPS-induced PGE2 production measured after 20 to 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460539(CHEMBL4225160)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50460539(CHEMBL4225160)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant human mPGES1 expressed in CHO cells assessed as reduction in PGE2 production using PGH2 as substrate incubated for 10 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300K5PubMed